Complement C3 Plays a Key Role in Inducing Humoral and Cellular Immune Responses to Influenza Virus Strain-Specific Hemagglutinin-Based or Cross-Protective M2 Extracellular Domain-Based Vaccination

The complement pathway is involved in eliminating antigen immune complexes. However, the role of the C3 complement system remains largely unknown in influenza virus M2 extracellular (M2e) domain or hemagglutinin (HA) vaccine-mediated protection after vaccination. Using a C3 knockout (C3 KO) mouse mo...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kim, Yu-Jin, Kim, Ki-Hye, Ko, Eun-Ju, Kim, Min-Chul, Lee, Yu-Na, Jung, Yu-Jin, Lee, Young-Tae, Kwon, Young-Man, Song, Jae-Min, Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158440/
https://ncbi.nlm.nih.gov/pubmed/30068650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00969-18
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