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A Mutation in the UL24 Gene Abolishes Expression of the Newly Identified UL24.5 Protein of Herpes Simplex Virus 1 and Leads to an Increase in Pathogenicity in Mice

Herpes simplex virus 1 (HSV-1) infects the host via epithelia and establishes latency in sensory neurons. The UL24 gene is conserved throughout the Herpesviridae family, and the UL24 protein is important for efficient viral replication and pathogenesis. Multiple transcripts are expressed from the UL...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Dridi, Slimane, Richerioux, Nicolas, Gonzalez Suarez, Carmen Elena, Vanharen, Marion, Sanabria-Solano, Carolina, Pearson, Angela
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158418/
https://ncbi.nlm.nih.gov/pubmed/30068651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00671-18
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