Herpes Simplex Virus Type 2 UL24 Gene Is a Virulence Determinant in Murine and Guinea Pig Disease Models

A herpes simplex virus type 2 (HSV-2) UL24 β-glucuronidase (UL24-βgluc) insertion mutant was derived from HSV-2 strain 186 via standard marker transfer techniques. Cell monolayers infected with UL24-βgluc yielded cytopathic effect with syncytium formation. UL24-βgluc replicated to wild-type viral ti...

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Detalhes bibliográficos
Main Authors: Blakeney, Susan, Kowalski, Jacek, Tummolo, Donna, DeStefano, Joanne, Cooper, David, Guo, Min, Gangolli, Seema, Long, Deborah, Zamb, Timothy, Natuk, Robert J., Visalli, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182662/
https://ncbi.nlm.nih.gov/pubmed/16051842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10498-10506.2005
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