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A Mutation in the UL24 Gene Abolishes Expression of the Newly Identified UL24.5 Protein of Herpes Simplex Virus 1 and Leads to an Increase in Pathogenicity in Mice

Herpes simplex virus 1 (HSV-1) infects the host via epithelia and establishes latency in sensory neurons. The UL24 gene is conserved throughout the Herpesviridae family, and the UL24 protein is important for efficient viral replication and pathogenesis. Multiple transcripts are expressed from the UL...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dridi, Slimane, Richerioux, Nicolas, Gonzalez Suarez, Carmen Elena, Vanharen, Marion, Sanabria-Solano, Carolina, Pearson, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158418/
https://ncbi.nlm.nih.gov/pubmed/30068651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00671-18
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