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Inhibition of glioblastoma cell proliferation, invasion, and mechanism of action of a novel hydroxamic acid hybrid molecule

Glioblastoma multiforme is one of the most aggressive brain tumors and current therapies with temozolomide or suberoylanilide hydroxamic acid (SAHA, vorinostat) show considerable limitations. SAHA is a histone deacetylase (HDAC) inhibitor that can cause undesirable side effects due to the lack of se...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Discov
Asıl Yazarlar: Zhang, Issan, Beus, Maja, Stochaj, Ursula, Le, Phuong Uyen, Zorc, Branka, Rajić, Zrinka, Petrecca, Kevin, Maysinger, Dusica
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158288/
https://ncbi.nlm.nih.gov/pubmed/30302275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0103-0
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