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Cell-penetrating Chaperone Peptide Prevents Protein Aggregation And Protects Against Cell Apoptosis

Many of the newly discovered therapeutic peptides and molecules are limited by their inability to cross the cell membrane. In the present study we employed a cell penetrating peptide (CPP), VPTLK, derived from Ku70 protein, to facilitate the entry of a mini-chaperone across the cell membrane. Our pr...

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Bibliografski detalji
Izdano u:Adv Biosyst
Glavni autori: Raju, Murugesan, Santhoshkumar, Puttur, Sharma, K. Krishna
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157914/
https://ncbi.nlm.nih.gov/pubmed/30271873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.201700095
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