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Implications of alternative routes to APC/C inhibition by the mitotic checkpoint complex
The mitotic checkpoint (also called spindle assembly checkpoint) is a signaling pathway that ensures faithful chromosome segregation. Mitotic checkpoint proteins inhibit the anaphase-promoting complex (APC/C) and its activator Cdc20 to prevent precocious anaphase. Checkpoint signaling leads to a com...
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| Publié dans: | PLoS Comput Biol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157902/ https://ncbi.nlm.nih.gov/pubmed/30199529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006449 |
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