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TRUmiCount: correctly counting absolute numbers of molecules using unique molecular identifiers
MOTIVATION: Counting molecules using next-generation sequencing (NGS) suffers from PCR amplification bias, which reduces the accuracy of many quantitative NGS-based experimental methods such as RNA-Seq. This is true even if molecules are made distinguishable using unique molecular identifiers (UMIs)...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157883/ https://ncbi.nlm.nih.gov/pubmed/29672674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty283 |
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