A neoepitope derived from a novel human germline APC gene mutation in familial adenomatous polyposis shows selective immunogenicity

Familial adenomatous polyposis (FAP) is an inherited condition arising from genetic defects in the Adenomatous polyposis coli (APC) gene. Carriers with mutations in the APC gene develop polyps in the colon and rectum which if not managed, transition into colon cancer. In this study, we identified a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Majumder, Snigdha, Shah, Rakshit, Elias, Jisha, Mistry, Yogesh, Coral, Karunakaran, Shah, Priyanka, Maurya, Anand Kumar, Mittal, Bharti, D’Silva, Jason K., Murugan, Sakthivel, Mahadevan, Lakshmi, Sathian, Rekha, Ramprasad, V. L., Chakraborty, Papia, Gupta, Ravi, Chaudhuri, Amitabha, Khanna-Gupta, Arati
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157866/
https://ncbi.nlm.nih.gov/pubmed/30256815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203845
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