A neoepitope derived from a novel human germline APC gene mutation in familial adenomatous polyposis shows selective immunogenicity

Familial adenomatous polyposis (FAP) is an inherited condition arising from genetic defects in the Adenomatous polyposis coli (APC) gene. Carriers with mutations in the APC gene develop polyps in the colon and rectum which if not managed, transition into colon cancer. In this study, we identified a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Majumder, Snigdha, Shah, Rakshit, Elias, Jisha, Mistry, Yogesh, Coral, Karunakaran, Shah, Priyanka, Maurya, Anand Kumar, Mittal, Bharti, D’Silva, Jason K., Murugan, Sakthivel, Mahadevan, Lakshmi, Sathian, Rekha, Ramprasad, V. L., Chakraborty, Papia, Gupta, Ravi, Chaudhuri, Amitabha, Khanna-Gupta, Arati
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157866/
https://ncbi.nlm.nih.gov/pubmed/30256815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0203845
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