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A novel dual-cytokine antibody fusion protein for the treatment of CD38-positive malignancies

A novel dual-cytokine antibody fusion protein, consisting of an antibody directed against CD38 [a tumor-associated antigen mainly expressed on the surface of multiple myeloma (MM) cells], simultaneously fused to both tumor necrosis factor ligand superfamily member 10 (TRAIL) and interleukin-2 (IL2),...

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Detalhes bibliográficos
Publicado no:Protein Eng Des Sel
Main Authors: De Luca, Roberto, Kachel, Paul, Kropivsek, Klara, Manz, Markus G., Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157721/
https://ncbi.nlm.nih.gov/pubmed/29982719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzy015
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