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A novel dual-cytokine antibody fusion protein for the treatment of CD38-positive malignancies
A novel dual-cytokine antibody fusion protein, consisting of an antibody directed against CD38 [a tumor-associated antigen mainly expressed on the surface of multiple myeloma (MM) cells], simultaneously fused to both tumor necrosis factor ligand superfamily member 10 (TRAIL) and interleukin-2 (IL2),...
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| Veröffentlicht in: | Protein Eng Des Sel |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157721/ https://ncbi.nlm.nih.gov/pubmed/29982719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzy015 |
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