Lysophosphatidic Acid Is Associated With Cardiac Dysfunction and Hypertrophy by Suppressing Autophagy via the LPA3/AKT/mTOR Pathway

Background: Lysophosphatidic acid (LPA), as a phospholipid signal molecule, participates in the regulation of various biological functions. Our previous study demonstrated that LPA induces cardiomyocyte hypertrophy in vitro; however, the functional role of LPA in the post-infarct heart remains unkno...

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Foilsithe in:Front Physiol
Main Authors: Yang, Jinjing, Xu, Jiyao, Han, Xuebin, Wang, Hao, Zhang, Yuean, Dong, Jin, Deng, Yongzhi, Wang, Jingping
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Physiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157396/
https://ncbi.nlm.nih.gov/pubmed/30283359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01315
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