DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival

OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is often associated with chronic systemic inflammation (SI). In the present study, we assessed if DNA methylation-derived SI (mdSI) indices: Neutrophil-to- Lymphocyte ratio (mdNLR) and Lymphocyte-to-Monocyte ratio (mdLMR) are associated with...

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Vydáno v:Oral Oncol
Hlavní autoři: Ambatipudi, Srikant, Langdon, Ryan, Richmond, Rebecca C., Suderman, Matthew, Koestler, Devin C., Kelsey, Karl T., Kazmi, Nabila, Penfold, Christopher, Ho, Karen M., McArdle, Wendy, Ring, Susan M., Pring, Miranda, Waterboer, Tim, Pawlita, Michael, Gaunt, Tom R., Davey Smith, George, Thomas, Steve, Ness, Andy R., Relton, Caroline L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156796/
https://ncbi.nlm.nih.gov/pubmed/30220325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2018.08.021
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