DNA methylation derived systemic inflammation indices are associated with head and neck cancer development and survival

OBJECTIVES: Head and neck squamous cell carcinoma (HNSCC) is often associated with chronic systemic inflammation (SI). In the present study, we assessed if DNA methylation-derived SI (mdSI) indices: Neutrophil-to- Lymphocyte ratio (mdNLR) and Lymphocyte-to-Monocyte ratio (mdLMR) are associated with...

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Pubblicato in:Oral Oncol
Autori principali: Ambatipudi, Srikant, Langdon, Ryan, Richmond, Rebecca C., Suderman, Matthew, Koestler, Devin C., Kelsey, Karl T., Kazmi, Nabila, Penfold, Christopher, Ho, Karen M., McArdle, Wendy, Ring, Susan M., Pring, Miranda, Waterboer, Tim, Pawlita, Michael, Gaunt, Tom R., Davey Smith, George, Thomas, Steve, Ness, Andy R., Relton, Caroline L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156796/
https://ncbi.nlm.nih.gov/pubmed/30220325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2018.08.021
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