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The long-term impact of folic acid in pregnancy on offspring DNA methylation: follow-up of the Aberdeen Folic Acid Supplementation Trial (AFAST)

BACKGROUND: It has been proposed that maternal folic-acid supplement use may alter the DNA-methylation patterns of the offspring during the in-utero period, which could influence development and later-life health outcomes. Evidence from human studies suggests a role for prenatal folate levels in inf...

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Dades bibliogràfiques
Publicat a:Int J Epidemiol
Autors principals: Richmond, Rebecca C, Sharp, Gemma C, Herbert, Georgia, Atkinson, Charlotte, Taylor, Caroline, Bhattacharya, Sohinee, Campbell, Doris, Hall, Marion, Kazmi, Nabila, Gaunt, Tom, McArdle, Wendy, Ring, Susan, Davey Smith, George, Ness, Andy, Relton, Caroline L
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005053/
https://ncbi.nlm.nih.gov/pubmed/29546377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ije/dyy032
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