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Computational modeling of synergistic interaction between αVβ3 integrin and VEGFR2 in endothelial cells: implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides
Cooperation between VEGFR2 and integrin αVβ3 is critical for neovascularization in wound healing, cardiovascular ischemic diseases, ocular diseases, and tumor angiogenesis. In the present study, we developed a rule- based computational model to investigate the potential mechanism by which the Src-in...
Zapisane w:
| Wydane w: | J Theor Biol |
|---|---|
| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156791/ https://ncbi.nlm.nih.gov/pubmed/30036530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2018.06.029 |
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