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Nrf1 can be processed and activated in a proteasome-independent manner
Vangala et al. demonstrate that the ER-bound transcription factor Nrf1 can be proteolytically cleaved and activated when the proteasome is completely inhibited, thus pointing to the existence of a proteasome-independent pathway to generate functional Nrf1.
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| Publicado en: | Curr Biol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156719/ https://ncbi.nlm.nih.gov/pubmed/27676297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2016.08.008 |
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