Plasmodium co-infection protects against chikungunya virus-induced pathologies

Co-infection with Plasmodium and chikungunya virus (CHIKV) has been reported in humans, but the impact of co-infection on pathogenesis remains unclear. Here, we show that prior exposure to Plasmodium suppresses CHIKV-associated pathologies in mice. Mechanistically, Plasmodium infection induces IFNγ,...

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Publicado en:Nat Commun
Main Authors: Teo, Teck-Hui, Lum, Fok-Moon, Ghaffar, Khairunnisa, Chan, Yi-Hao, Amrun, Siti Naqiah, Tan, Jeslin J. L., Lee, Cheryl Y. P., Chua, Tze-Kwang, Carissimo, Guillaume, Lee, Wendy W. L., Claser, Carla, Rajarethinam, Ravisankar, Rénia, Laurent, Ng, Lisa F. P.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156405/
https://ncbi.nlm.nih.gov/pubmed/30254309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06227-9
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