Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods

Many reprogramming methods can generate human induced pluripotent stem cells (hiPSCs) that closely resemble human embryonic stem cells (hESCs). This has led to assessments of how similar hiPSCs are to hESCs, by evaluating differences in gene expression, epigenetic marks and differentiation potential...

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Detalhes bibliográficos
Publicado no:Nat Biomed Eng
Main Authors: Churko, Jared M., Lee, Jaecheol, Ameen, Mohamed, Gu, Mingxia, Venkatasubramanian, Meenakshi, Diecke, Sebastian, Sallam, Karim, Im, Hogune, Wang, Gavin, Gold, Joseph D., Salomonis, Nathan, Snyder, Michael P., Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155993/
https://ncbi.nlm.nih.gov/pubmed/30263871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-017-0141-6
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