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Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives

In this study, a series of regioisomeric acetylenic sulfamoylquinolines are designed, synthesized, and tested in vitro for their antiproliferative activity against three human breast cacer cell lines (T47D, MCF-7, and MDA-MB-231) and a human normal fibroblast (HFF-1) by 4-[3-(4-iodophenyl)-2-(4-nitr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Marciniec, Krzysztof, Pawełczak, Bartosz, Latocha, Małgorzata, Skrzypek, Leszek, Maciążek-Jurczyk, Małgorzata, Boryczka, Stanisław
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155812/
https://ncbi.nlm.nih.gov/pubmed/28212337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020300
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