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New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity
Betulin 1 and its semisynthetic derivatives exhibit a cytotoxic activity toward various cancer cell lines. These compounds are a promising and potential anticancer candidates. A series of betulin derivatives was prepared and tested for the antiproliferative activity in vitro against T47D breast canc...
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Publicado no: | Med Chem Res |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5219024/ https://ncbi.nlm.nih.gov/pubmed/28111514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00044-016-1713-9 |
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