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Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde

A series of 3-substituted derivatives of betulin and betulinic aldehyde were synthesized as promising anticancer agents. The newly triterpenes were tested against five human cancer cell lines like biphenotypic B myelomonocytic leukaemia (MV-4-11), adenocarcinoma (A549), prostate (Du-145), melanoma (...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bębenek, Ewa, Chrobak, Elwira, Marciniec, Krzysztof, Kadela-Tomanek, Monika, Trynda, Justyna, Wietrzyk, Joanna, Boryczka, Stanisław
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471197/
https://ncbi.nlm.nih.gov/pubmed/30893801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061372
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