New Phosphorus Analogs of Bevirimat: Synthesis, Evaluation of Anti-HIV-1 Activity and Molecular Docking Study

Since the beginning of the human immunodeficiency virus (HIV) epidemic, many groups of drugs characterized by diverse mechanisms of action have been developed, which can suppress HIV viremia. 3-O-(3′,3′-Dimethylsuccinyl) betulinic acid, known as bevirimat (BVM), was the first compound in the class o...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Chrobak, Elwira, Marciniec, Krzysztof, Dąbrowska, Aleksandra, Pęcak, Paweł, Bębenek, Ewa, Kadela-Tomanek, Monika, Bak, Andrzej, Jastrzębska, Maria, Boryczka, Stanisław
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6829466/
https://ncbi.nlm.nih.gov/pubmed/31640137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205209
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