Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma

Two kinds of naphthalimide derivatives were synthesized and evaluated for in vitro their anti-hepatocellular carcinoma properties. Compound 3a with a fused thiazole fragment to naphthalimide skeleton inhibited cell migration of SMMC-7721 and HepG2, and further in vivo trials with two animal models c...

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Gepubliceerd in:Molecules
Hoofdauteurs: Ge, Chaochao, Chang, Liping, Zhao, Ying, Chang, Congcong, Xu, Xiaojuan, He, Haoying, Wang, Yuxia, Dai, Fujun, Xie, Songqiang, Wang, Chaojie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155709/
https://ncbi.nlm.nih.gov/pubmed/28241441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22020342
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