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Synthesis and Biological Evaluation of Novel Aromatic Imide-Polyamine Conjugates

Three types of conjugates in which aromatic imide scaffolds were coupled to diverse amine/polyamine motifs were synthesized, and their antitumor activities were evaluated in vitro and in vivo. Results showed that the conjugate 11e of 1,8-naphthilimide with spermine had pronounced effects on inhibiti...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Li, Ming, Wang, Yuxia, Zhang, Jianying, Xie, Songqiang, Wang, Chaojie, Wu, Yingliang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273765/
https://ncbi.nlm.nih.gov/pubmed/27916902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121637
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