Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation

Glucocorticoids (GCs) are currently used for the therapeutic management of cholestatic diseases, but their use and molecular mechanism remain controversial. The aims of this study were 1) to assess the therapeutic effect of a 2-week treatment with the GC dexamethasone on hepatic damage in bile duct-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gabbia, Daniela, Pozzo, Luisa, Zigiotto, Giorgia, Roverso, Marco, Sacchi, Diana, Dalla Pozza, Arianna, Carrara, Maria, Bogialli, Sara, Floreani, Annarosa, Guido, Maria, De Martin, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155538/
https://ncbi.nlm.nih.gov/pubmed/30252871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204336
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