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Analysis of the role of GSK3 in the mitotic checkpoint

The mitotic checkpoint ensures proper chromosome segregation; defects in this checkpoint can lead to aneuploidy, a hallmark of cancer. The mitotic checkpoint blocks progression through mitosis as long as chromosomes remain unattached to spindle microtubules. Unattached kinetochores induce the format...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Rashid, M. S., Mazur, T., Ji, W., Liu, S. T., Taylor, W. R.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155330/
https://ncbi.nlm.nih.gov/pubmed/30250048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32435-w
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