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Comparison of the Sulfonamide Inhibition Profiles of the β- and γ-Carbonic Anhydrases from the Pathogenic Bacterium Burkholderia pseudomallei

We have cloned, purified, and characterized a β-carbonic anhydrase (CA, EC 4.2.1.1), BpsCAβ, from the pathogenic bacterium Burkholderia pseudomallei, responsible for the tropical disease melioidosis. The enzyme showed high catalytic activity for the physiologic CO(2) hydration reaction to bicarbonat...

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Vydáno v:Molecules
Hlavní autoři: Vullo, Daniela, Del Prete, Sonia, Di Fonzo, Pietro, Carginale, Vincenzo, Donald, W. Alexander, Supuran, Claudiu T., Capasso, Clemente
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155308/
https://ncbi.nlm.nih.gov/pubmed/28272358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22030421
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