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Comparison of the Sulfonamide Inhibition Profiles of the β- and γ-Carbonic Anhydrases from the Pathogenic Bacterium Burkholderia pseudomallei

We have cloned, purified, and characterized a β-carbonic anhydrase (CA, EC 4.2.1.1), BpsCAβ, from the pathogenic bacterium Burkholderia pseudomallei, responsible for the tropical disease melioidosis. The enzyme showed high catalytic activity for the physiologic CO(2) hydration reaction to bicarbonat...

詳細記述

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書誌詳細
出版年:Molecules
主要な著者: Vullo, Daniela, Del Prete, Sonia, Di Fonzo, Pietro, Carginale, Vincenzo, Donald, W. Alexander, Supuran, Claudiu T., Capasso, Clemente
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155308/
https://ncbi.nlm.nih.gov/pubmed/28272358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22030421
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