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Comparison of the Sulfonamide Inhibition Profiles of the β- and γ-Carbonic Anhydrases from the Pathogenic Bacterium Burkholderia pseudomallei

We have cloned, purified, and characterized a β-carbonic anhydrase (CA, EC 4.2.1.1), BpsCAβ, from the pathogenic bacterium Burkholderia pseudomallei, responsible for the tropical disease melioidosis. The enzyme showed high catalytic activity for the physiologic CO(2) hydration reaction to bicarbonat...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Vullo, Daniela, Del Prete, Sonia, Di Fonzo, Pietro, Carginale, Vincenzo, Donald, W. Alexander, Supuran, Claudiu T., Capasso, Clemente
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155308/
https://ncbi.nlm.nih.gov/pubmed/28272358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22030421
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