A similar effect of P16 hydroxymethylation and true-methylation on the prediction of malignant transformation of oral epithelial dysplasia: observation from a prospective study

BACKGROUND: Total P16 methylation (P16M), including P16 hydroxymethylation (P16H) and true-P16M, correlates with malignant transformation of oral epithelial dysplasia (OED). Both true-P16M and P16H are early events in carcinogenesis. The aim of this study is to prospectively determine if discriminat...

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Vydáno v:BMC Cancer
Hlavní autoři: Liu, Hongwei, Liu, Zhaojun, Liu, Xue-wei, Xu, Si, Wang, Lei, Liu, Yang, Zhou, Jing, Gu, Liankun, Gao, Yan, Liu, Xiao-yong, Shi, Huidong, Sun, Zheng, Deng, Dajun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154879/
https://ncbi.nlm.nih.gov/pubmed/30249192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4787-6
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