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Local unwinding of double-strand DNA ends by the MRX complex promotes Exo1 processing activity
Homologous recombination is initiated by nucleolytic degradation (resection) of DNA double-strand breaks (DSBs), which involves different nucleases including the Mre11-Rad50-Xrs2 (MRX) complex and the Exonuclease 1 (Exo1). The characterization of a novel mutation in Mre11 causing accelerated DSB res...
Enregistré dans:
| Publié dans: | Mol Cell Oncol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154851/ https://ncbi.nlm.nih.gov/pubmed/30263949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1511208 |
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