Autophagy as a mechanism of Apo2L/TRAIL resistance

Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is unique to selectively induce apoptosis in tumor cells while sparing normal cells. Thus there is tremendous interest in Apo2L/TRAIL therapy; however, drug resistance is a serious limitation. Autophagy is a cellular...

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Vydáno v:Cancer Biol Ther
Hlavní autoři: Sharma, Arishya, Almasan, Alexandru
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154847/
https://ncbi.nlm.nih.gov/pubmed/30067424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1472191
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