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TRAIL/Apo-2L: Mechanisms and Clinical Applications in Cancer
TNF-related apoptosis-inducing ligand (TRAIL/APO-2L) is a member of the TNF family that promotes apoptosis by binding to the transmembrane receptors TRAIL-R1/DR4 and TRAIL-R2/DR5. Its cytotoxic activity is relatively selective to the human tumor cell lines without much effect on the normal cells. He...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1506567/ https://ncbi.nlm.nih.gov/pubmed/11774036 |
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