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Autophagy as a mechanism of Apo2L/TRAIL resistance

Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is unique to selectively induce apoptosis in tumor cells while sparing normal cells. Thus there is tremendous interest in Apo2L/TRAIL therapy; however, drug resistance is a serious limitation. Autophagy is a cellular...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Sharma, Arishya, Almasan, Alexandru
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154847/
https://ncbi.nlm.nih.gov/pubmed/30067424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1472191
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