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A mechanism of resistance to TRAIL/Apo2L-induced apoptosis of newly established glioma cell line and sensitisation to TRAIL by genotoxic agents

Most tumour cells are sensitive to TRAIL-induced apoptosis, but not normal cells; thus, cancer therapy using TRAIL is expected clinically. Several tumour cells are resistant to TRAIL-induced apoptosis, and various mechanisms of such resistance were reported in individual cases. In this study, we est...

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Autori principali: Arizono, Y, Yoshikawa, H, Naganuma, H, Hamada, Y, Nakajima, Y, Tasaka, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2377044/
https://ncbi.nlm.nih.gov/pubmed/12610517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600666
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