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Non-Anticoagulant Heparins Are Hepcidin Antagonists for the Treatment of Anemia
The peptide hormone hepcidin is a key controller of systemic iron homeostasis, and its expression in the liver is mainly regulated by bone morphogenetic proteins (BMPs), which are heparin binding proteins. In fact, heparins are strong suppressors of hepcidin expression in hepatic cell lines that act...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154463/ https://ncbi.nlm.nih.gov/pubmed/28397746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22040598 |
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