Glycol-split nonanticoagulant heparins are inhibitors of hepcidin expression in vitro and in vivo

Hepcidin controls systemic iron availability, and its excess contributes to the anemia of chronic diseases, the most prevalent anemia in hospitalized patients. We previously reported that heparins are efficient hepcidin inhibitors both in vitro and in vivo, but their anticoagulant activity limits th...

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Detalhes bibliográficos
Main Authors: Poli, Maura, Asperti, Michela, Naggi, Annamaria, Campostrini, Natascia, Girelli, Domenico, Corbella, Michela, Benzi, Marina, Besson-Fournier, Celine, Coppin, Helene, Maccarinelli, Federica, Finazzi, Dario, Arosio, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945865/
https://ncbi.nlm.nih.gov/pubmed/24398330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-515221
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