Oral adsorbent AST-120 ameliorates gut environment and protects against the progression of renal impairment in CKD rats

BACKGROUND: Oral charcoal adsorbent AST-120 (AST) is reported to ameliorate renal dysfunction by the absorption of toxic substance in the gut. Recent study revealed that, in CKD, gut environment is disturbed including the decrease in tight junctions and Lactobacillus (Lact). In this study, we examin...

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Bibliographic Details
Published in:Clin Exp Nephrol
Main Authors: Yoshifuji, Ayumi, Wakino, Shu, Irie, Junichiro, Matsui, Ayumi, Hasegawa, Kazuhiro, Tokuyama, Hirobumi, Hayashi, Koichi, Itoh, Hiroshi
Format: Artigo
Language:Inglês
Published: Springer Singapore 2018
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6154091/
https://ncbi.nlm.nih.gov/pubmed/29675795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-018-1577-z
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