The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction.

An accelerated progressive decline in renal function is a frequent accompaniment of myocardial infarction (MI). Indoxyl sulfate (IS), a uremic toxin that accumulates from the early stages of chronic kidney disease (CKD), is contributory to both renal and cardiac fibrosis. IS levels can be reduced by...

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Bibliographic Details
Main Authors: Suree Lekawanvijit, Sirinart Kumfu, Bing H Wang, Minako Manabe, Fuyuhiko Nishijima, Darren J Kelly, Henry Krum, Andrew R Kompa
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3862807?pdf=render
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