Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients

BACKGROUND: To deliver efficacious personalised cancer treatment, it is essential to characterise the cellular metabolism as well as the genetic stability of individual tumours. In this study, we describe a new axis between DNA repair and detoxification of aldehyde derivatives with important implica...

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Publicat a:Cell Oncol (Dordr)
Autors principals: Chen, Xin, Legrand, Arnaud J., Cunniffe, Siobhan, Hume, Samuel, Poletto, Mattia, Vaz, Bruno, Ramadan, Kristijan, Yao, Dengfu, Dianov, Grigory L.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2018
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153960/
https://ncbi.nlm.nih.gov/pubmed/30088263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-018-0390-8
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