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Synthesis and Excellent Duplex Stability of Oligonucleotides Containing 2′-Amino-LNA Functionalized with Galactose Units

A convenient method for the preparation of oligonucleotides containing internally-attached galactose and triantennary galactose units has been developed based on click chemistry between 2′-N-alkyne 2′-amino-LNA nucleosides and azido-functionalized galactosyl building blocks. The synthesized oligonuc...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Kumar, Rajesh, Ries, Annika, Wengel, Jesper
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153924/
https://ncbi.nlm.nih.gov/pubmed/28531137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22050852
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