Population Pharmacokinetics of the Antimalarial Amodiaquine: a Pooled Analysis To Optimize Dosing

Amodiaquine plus artesunate is the recommended antimalarial treatment in many countries where malaria is endemic. However, pediatric doses are largely based on a linear extrapolation from adult doses. We pooled data from previously published studies on the pharmacokinetics of amodiaquine, to optimiz...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ali, Ali Mohamed, Penny, Melissa A., Smith, Thomas A., Workman, Lesley, Sasi, Philip, Adjei, George O., Aweeka, Francesca, Kiechel, Jean-René, Jullien, Vincent, Rijken, Marcus J., McGready, Rose, Mwesigwa, Julia, Kristensen, Kim, Stepniewska, Kasia, Tarning, Joel, Barnes, Karen I., Denti, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153844/
https://ncbi.nlm.nih.gov/pubmed/30038039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02193-17
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