Population Pharmacokinetic and Pharmacodynamic Modeling of Amodiaquine and Desethylamodiaquine in Women with Plasmodium vivax Malaria during and after Pregnancy

Amodiaquine is effective for the treatment of Plasmodium vivax malaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria. This study evaluated the population pharmacokinetic and pharmacodynamic properties of amodiaqui...

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Main Authors: Tarning, Joel, Chotsiri, Palang, Jullien, Vincent, Rijken, Marcus J., Bergstrand, Martin, Cammas, Mireille, McGready, Rose, Singhasivanon, Pratap, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois, Lindegardh, Niklas
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486620/
https://ncbi.nlm.nih.gov/pubmed/22926572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01242-12
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