Population Pharmacokinetic and Pharmacodynamic Modeling of Amodiaquine and Desethylamodiaquine in Women with Plasmodium vivax Malaria during and after Pregnancy

Amodiaquine is effective for the treatment of Plasmodium vivax malaria, but there is little information on the pharmacokinetic and pharmacodynamic properties of amodiaquine in pregnant women with malaria. This study evaluated the population pharmacokinetic and pharmacodynamic properties of amodiaqui...

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Main Authors: Tarning, Joel, Chotsiri, Palang, Jullien, Vincent, Rijken, Marcus J., Bergstrand, Martin, Cammas, Mireille, McGready, Rose, Singhasivanon, Pratap, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois, Lindegardh, Niklas
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486620/
https://ncbi.nlm.nih.gov/pubmed/22926572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01242-12
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