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Genetic and Biochemical Characterization of OXA-535, a Distantly Related OXA-48-Like β-Lactamase

OXA-535 is a chromosome-encoded carbapenemase of Shewanella bicestrii JAB-1 that shares only 91.3% amino acid sequence identity with OXA-48. Catalytic efficiencies are similar to those of OXA-48 for most β-lactams, except for ertapenem, where a 2,000-fold-higher efficiency was observed with OXA-535....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Dabos, L., Jousset, A. B., Bonnin, R. A., Fortineau, N., Zavala, A., Retailleau, P., Iorga, B. I., Naas, T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153822/
https://ncbi.nlm.nih.gov/pubmed/30082287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01198-18
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