Genetic and Biochemical Characterization of OXA-519, a Novel OXA-48-Like β-Lactamase

A multidrug-resistant Klebsiella pneumoniae 1210 isolate with reduced carbapenem susceptibility revealed the presence of a novel plasmid-encoded bla(OXA-48-like) gene, named bla(OXA-519). The 60.7-kb plasmid (pOXA-519) was similar to the IncL-OXA-48 prototypical plasmid except for a ca. 2-kb deletio...

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發表在:Antimicrob Agents Chemother
Main Authors: Dabos, Laura, Bogaerts, Pierre, Bonnin, Remy A., Zavala, Agustin, Sacré, Pierre, Iorga, Bogdan I., Huang, Daniel T., Glupczynski, Youri, Naas, Thierry
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Mechanisms of Resistance
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105830/
https://ncbi.nlm.nih.gov/pubmed/29866857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00469-18
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