Effect of Pregnancy on the Pharmacokinetic Interaction between Efavirenz and Lumefantrine in HIV-Malaria Coinfection

Artemether-lumefantrine is often coadministered with efavirenz-based antiretroviral therapy for malaria treatment in HIV-infected women during pregnancy. Previous studies showed changes in lumefantrine pharmacokinetics due to interaction with efavirenz in nonpregnant adults. The influence of pregnan...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Adegbola, Adebanjo, Abutaima, Rana, Olagunju, Adeniyi, Ijarotimi, Omotade, Siccardi, Marco, Owen, Andrew, Soyinka, Julius, Bolaji, Oluseye
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153791/
https://ncbi.nlm.nih.gov/pubmed/30082286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01252-18
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