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The Role of α-sheet in Amyloid Oligomer Aggregation and Toxicity

A major barrier to developing effective treatments and diagnostics for amyloid diseases is the inability of traditional protein structure characterization methods to elucidate the structure of the toxic oligomers that form during amyloidogenesis. Some years ago, our lab “discovered” a novel protein...

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Bibliografiske detaljer
Udgivet i:Yale J Biol Med
Main Authors: Bi, Timothy M., Daggett, Valerie
Format: Artigo
Sprog:Inglês
Udgivet: YJBM 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153628/
https://ncbi.nlm.nih.gov/pubmed/30258312
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