X-ray structural analyses of azide-bound cytochrome c oxidases reveal that the H-pathway is critically important for the proton-pumping activity

Cytochrome c oxidase (CcO) is the terminal oxidase of cellular respiration, reducing O(2) to water and pumping protons. X-ray structural features have suggested that CcO pumps protons via a mechanism involving electrostatic repulsions between pumping protons in the hydrogen-bond network of a proton-...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Shimada, Atsuhiro, Hatano, Keita, Tadehara, Hitomi, Yano, Naomine, Shinzawa-Itoh, Kyoko, Yamashita, Eiki, Muramoto, Kazumasa, Tsukihara, Tomitake, Yoshikawa, Shinya
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Bioenergetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153300/
https://ncbi.nlm.nih.gov/pubmed/30077971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003123
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